Brinox Farmacinė Chromatografijos Ir Cip Sistema pirkti naudotą (21 632)

Būklė: naujas, Gamybos metai: 2020, Funkcionalumas: visiškai funkcionalus, Įranga: dokumentacija / vadovas, Package 15 PP6715 – CS6715 Brinox LEP 11 – Pharma Chromatography and CIP System New – Factory Sealed – Factory New Manufacturer: Brinox Model: LEP 11 Configuration: PP6715 with CIP System CS6715 Condition: New, unused, original packaging Description For sale is a high-quality pharmaceutical chromatography system Brinox LEP 11 consisting of panel PP6715 and the associated CIP unit CS6715. The system is completely new, unused, and in the original manufacturer condition. It was designed for industrial C1-INH chromatography and complies with the highest GMP standards. Functionality - Slurry transfer - Washing and elution processes - Transfer to pre-precipitation tanks - Gel disposal Hsdpfx Aeyl Rqpoftonn - Autonomous CIP circuit Technical Specifications - Wetted parts: stainless steel 1.4435 - Electropolished, Ra ≤ 0.8 µm - FDA-compliant sealing systems - Suitable for CIP/SIP - Operating pressure up to 6 bar - Temperature range up to 95 °C - Completely drainable piping CIP Skid CS6715 - Stainless steel frame - Centrifugal pump - Shell-and-tube heat exchanger - Cleaning media temperature control - Adjustable supply pressure The system is in mint factory condition with zero operating hours.

Gamybos metai: 2020, būklė: naujas, Funkcionalumas: visiškai funkcionalus, Įranga: dokumentacija / vadovas, Package 14 PP6713 – CS6713 Brinox LEP 11 – GMP Chromatography System with CIP Skid New – unused – original packaging Manufacturer: Brinox Model: LEP 11 Version: PP6713 with CIP System CS6713 Condition: New – in original packaging – never installed Description Offered is a pharmaceutical chromatography system LEP 11, consisting of the chromatography panel PP6713 and the corresponding CIP skid CS6713. The system is completely new, unused, and in its original manufacturer condition. The unit was designed for GMP protein purification within C1-INH chromatography processes. Plant Technology - Cleanroom panel for wall integration - Transfer lines to false-bottom vessels - Precipitation vessel connection - Gel waste line - Complete utility piping Technical Specifications - Design pressure: –0.9 to +6 bar - Design temperature: +2 to +95 °C - Electropolished surfaces Ra ≤ 0.8 µm Hedpfsyl Rnnsx Aftsnn - Material: 1.4435 (stainless steel) - Fully drainable - GMP compliant design CIP System CS6713 - Stainless steel frame construction - Centrifugal pump - Shell-and-tube heat exchanger - Conductivity, pressure, and temperature monitoring - Adjustable CIP feed The system is factory-new and has never been commissioned.

Būklė: naujas, Gamybos metai: 2020, Funkcionalumas: visiškai funkcionalus, Įranga: dokumentacija / vadovas, Brinox LEP 11 – Pharmaceutical Chromatography System with CIP System New, unused, original packaging Manufacturer: Brinox Model: LEP 11 Configuration: PP6711 with associated CIP unit CS6711 Condition: New – unused – factory sealed (Factory New Condition) Description For sale is a Brinox LEP 11 pharmaceutical chromatography system, comprising the chromatography panel PP6711 and the associated CIP unit CS6711. The system is completely new, unused, and in its original packaging. It was engineered, manufactured, and delivered, but never installed or commissioned. The unit is designed for C1-INH chromatography and is intended for controlled protein purification using sieve bottom vessels in a GMP environment. Process Functions - Transfer of loaded QAE gel (slurry) - Washing and elution processes - Transfer of eluate to pre-precipitation vessels - Gel disposal via container station Hnjdpfx Aeyl Ndnoftsn - Fully automatic CIP and SIP cleaning Technical Data - Fully CIP and SIP capable - Design pressure: –0.9 to +6 bar - Design temperature: +2 °C to +95 °C - Flow rates up to 10 m³/h - Adjustable slurry delivery 0.2 – 3 m³/h Specification - Product-contact parts stainless steel 1.4435 - Electropolished Ra ≤ 0.8 µm - FDA and EU compliant seals - Residual drainable construction - Cleanroom panel with Tri-Clamp connections - Magnetically monitored connection bend sections - 0.2 µm vent filter CIP Unit CS6711 - Compact stainless steel skid - Centrifugal pump - Shell-and-tube heat exchanger - Adjustable operating pressure - GMP compliant design The system is in factory new condition and has never been in production use.

Būklė: labai geros būklės (naudotas), Here we offer an ICS system. Flow rate range: 0.000 to 10.000 ml/min (analytical); 0.000 to 3.000 ml/min (capillary) Flow rate accuracy: < 0.1% Hnedpfx Ajzdtlfsftjn Flow rate precision: < 0.1% Accuracy and precision of gradient dosing: ±0.5% at 2 ml/min (analytical only) Pressure range: 0 to 35 MPa (0 to 5,000 psi) (analytical); 0 to 41 MPa (0 to 6,000 psi) (capillary) Dimensions (H x W x D): 14 x 8.25 x 19 in. (36 x 21 x 48 cm) Weight: 24.1 kg (55 lb.) (ICS-5000) Power supply: 9 to 265 V AC, 47 to 63 Hz The system consists of the following components: - ICS-5000 plus Dual Pump - 6-port valve MXP9900-000 - AFC-3000 Automated Fraction Collector - RFC-10 Controller Condition: used Scope of delivery: (See images as shown) (Technical specifications are subject to change and errors excepted!) If you have any further questions, we are happy to assist you by phone.

Būklė: naudotas, CIP sistema su 5 talpyklomis (vienas iš jų izoliuotas). Kitos sudedamosios dalys: - Kiekvienas talpykla su mėginių paėmimo čiaupais, kopėčių laikikliais, žmogaus anga viršuje, pneumatiniais vožtuvais ir lygio zondais - Vamzdinio pluošto šilumokaitis vandeniui šildyti; vanduo po to nukreipiamas į CIP talpyklas - 3 x dozavimo siurbliai (Grundfos) - CIP pirminis siurblys (Hilge) - Integruotas temperatūros ir laidumo matavimas - Vamzdžių panelės bei įvairios vamzdynų dalys, vožtuvai ir armatūra Mašina (papildomai): valymo sistema su 5 talpyklomis Medžiaga: talpyklos iš nerūdijančio plieno Padėtis / vieta: kiekviena talpykla ant 3 kojų Hnedpfx Ajy Tizwefton Pagrindinė konstrukcija: žemo kūgio formos talpyklos Įranga: 5 CIP talpyklos (1 iš jų su izoliacija); pirminis siurblys; 3 dozavimo siurbliai chemikalams; vamzdinio pluošto šilumokaitis; lygio zondai; temperatūros matavimas; laidumo matavimas; pneumatiniai diskiniai vožtuvai; vamzdžių panelės; kiti įvairūs vožtuvai, vamzdynai ir armatūra.

Gamybos metai: 1990, būklė: naudotas, CIP įranga Seitz kombinuotam filtrui, pagaminimo metai 1990. Rankinė sistema sudaryta iš šarmo talpos, šilumokaičio ir cirkuliacinio siurblio. Hnodpfxow Uc Hbe Afton Mašina (papildomai): 1 karštas bakas CIP bakas: 1500 l

Būklė: naudotas, CIP (Cleaning-in-Place) sistema, skirtas uždarai procesinių įrenginių valymui. Susideda iš stačiakampio formos rezervuaro, padalinto į 2 kameras. Kiekvienai kamerai numatytas nuimamas dangtis ir išleidimo linija su rankiniu vožtuvu. Komplektuojamas su dozavimo siurbliais rūgščiai, šarmui ir dezinfekavimo priemonei, taip pat išcentriniu siurbliu kaip CIP recirkuliacijos siurbliu. Mašina (papildomai): su 2 stačiakampėmis kameromis Hnodpfxsxbptmo Aften Ilgis: 3,7 m Plotis: 0,5 m Aukštis: 1,5 m Valdymas / kontrolė: rankinė Medžiaga: nerūdijantis plienas Įranga: stačiakampis rezervuaras su 2 kameromis, vožtuvai (visi rankiniai svertai), recirkuliacijos siurblys, dozavimo siurbliai Svoris: 300 kg

Būklė: naudotas, Šis skelbimas yra apie 1 iš 2 GE Healthcare ÄKTA process skystosios chromatografijos sistemų. Įrenginys yra visiškai veikiantis ir paruoštas nedelsiant naudoti. Sandėlyje turime panašios konfigūracijos sistemas, įskaitant Cytiva Akta Process 1 bei Cytiva Akta Process 2 skystosios chromatografijos sistemas. Įrangą galima apžiūrėti iš anksto susitarus Duxforde. GE Healthcare ÄKTAprocess – tai visiškai automatizuota skystosios chromatografijos sistema, skirta procesų didinimui ir stambaus masto biofarmacijos gamybai. Su plačiomis konfigūracijų galimybėmis, ši sistema leidžia sklandžiai pereiti nuo mažo masto ÄKTAexplorer ir ÄKTApilot sistemų prie pramoninės gamybos. Naudojant UNICORN valdymo programinę įrangą, atitinkančią reguliacinius reikalavimus, ir našų skysčių valdymą, ÄKTAprocess yra būtinas įrankis biofarmacijos gamybai. Pagrindinės savybės: Pažangi automatika ir valdymas: ● Automatinė skystosios chromatografijos sistema – užtikrina tikslų ir atkuriamą atskyrimą. ● UNICORN valdymo programinė įranga – intuityvus procesų valdymas ir stebėjimas. ● Konfigūracijos galimybės po pirkimo – lemia didesnį funkcionalumą ir ilgesnį tarnavimo laiką. Plastumas ir universalumas: ● Sukurta didelio masto biopramonei – palaiko sklandų perėjimą nuo laboratorijos prie gamybos. ● Individualiai pritaikoma – tūkstančiai galimų konfigūracijų įvairioms reikmėms. ● Trys srauto greičio diapazonai – našumas iki 1800 l/val. dideliems gamybos poreikiams. Kokybė ir atitiktis: ● Gamyboje naudojamos USP VI klasės medžiagos – atsekama, reguliacinius reikalavimus atitinkanti konstrukcija. ● Intelektualus AxiChrom kolonų pripildymas – užtikrina optimalų atskyrimą. ● Visi reguliaminiai dokumentai ir paslaugos – atitinka cGMP standartus. Kompaktiškas ir patogus naudoti dizainas: ● Integruotas kompiuteris – sumažina įrangos užimamą plotą ir tvarko darbo vietą. ● Patikima ir tvirta konstrukcija – skirta ilgalaikiam naudojimui pramoninėje aplinkoje. Techninės specifikacijos: Hedpfx Ajxxycgeftenn ● Svoris 450 kg ● Matmenys (cm): 41 Ilg. × 33 Pl. × 64 Aukš. ● Matmenys (coliais): 16 Ilg. × 13 Pl. × 25 Aukš. Privalumai: ● Optimizuota bio-procesų mastelio didinimui – pereikite nuo mažo iki pramoninio masto. ● Reguliacinė atitiktis – atitinka cGMP reikalavimus, pateikiama visa dokumentacija. ● Didelis konfigūruojamumas – lengvai pritaikoma įvairiems biopramonės poreikiams. ● Taupanti vietą konstrukcija – integruotas kompiuteris sumažina darbo vietos poreikius. Pritaikymo sritys: ÄKTAprocess idealiai tinka biofarmacijos gamybai, įskaitant: ● Monokloninių antikūnų gryninimą ● Vakcinų gamybą ● Rekombinantinių baltymų gryninimą ● Gydymo genais ir ląstelių terapijos procesus

Būklė: labai geros būklės (naudotas), Funkcionalumas: visiškai funkcionalus, CIP Installation by Westfalia Separator AG CIP Installation by Westfalia Separator AG | Tank, Pump, Heat Exchanger System type: CIP (Cleaning In Place) Manufacturer: Westfalia Separatoren AG / GEA Group A complete CIP (Cleaning In Place) installation from the renowned manufacturer Westfalia Separator AG, designed for automatic washing and disinfection of processing lines in the food and dairy industry. The system is equipped with stainless steel tanks with a heating jacket, recirculation pumps, a GEA Ecoflex plate heat exchanger, and a control cabinet. Main components of the installation: 1. CIP stainless steel tanks Brand: Westfalia Separator AG Type: CIP-TANK 3000 L (2 pcs.) Serial numbers: 96/00408-1 and 96/00408-2 Year of manufacture: 1996 Capacity: (2×) 3300 liters Operating pressure: 0 bar Operating temperature: 80 °C Dimensions: (2×) 3000 × 1900 × 2300 mm 2. Stainless steel platform with stairs Dimensions: 2950 × 2200 × 2400 mm 3. Stairs Dimensions: 600 × 600 × 500 mm 4. Centrifugal pump Brand: Hilge Type: EURO-HYGIA-B-SUPER-II/60 B Number: 23/96/11349 Capacity: 30 m³/h Power: 11.0 kW Dimensions: 750 × 350 × 450 mm 5. Flowmeter Brand: Endress + Hauser Model: Promag 53 Dimensions: 350 × 200 × 200 mm Precise flow measurement for CIP media 6. Anema centrifugal pump Dimensions: 530 × 300 × 300 mm 7. Plate heat exchanger Brand: GEA Ecoflex GmbH Type: VT20 CDS Serial number: 170/13832 Dimensions: 900 × 550 × 1500 mm High heat exchange efficiency for CIP solution preparation 8. Control cabinet Dimensions: 670 × 220 × 800 mm Responsible for control and monitoring of the CIP system operation 9. Stainless steel buffer tank (CIP tank) Tank dimensions: Ø 800 × 800 mm Overall dimensions: 1150 × 900 × 1770 mm 10. Anema centrifugal pump, number: 32078 Operating pressure: 12 bar Hedjxtvb Ujpfx Aftenn Dimensions: 650 × 400 × 450 mm The Westfalia Separatoren AG CIP installation is a complete solution for process equipment cleaning, providing: - high process hygiene, - washing parameter control (temperature, flow, time), - possibility of integration with dairy, food, or beverage production lines. The use of components from brands such as GEA, Hilge, Endress + Hauser, and Anema ensures reliability and long service life of the system.

Būklė: naudotas, Šiame pasiūlyme parduodama ÄKTA ready™ chromatografijos sistema Įrenginys yra visiškai veikiantis ir paruoštas nedelsiant naudoti. Hnodpfx Afsyhhgajten ÄKTA ready™ chromatografijos sistema – tai vienkartinio naudojimo skysčių chromatografijos platforma, sukurta bioprocesams, procesų mastelio didinimui ir GMP reikalavimus atitinkančiai biologinių vaistų, įskaitant monokloninius antikūnus, rekombinantinius baltymus, virusinius vektorius, nukleorūgštis ir kitus jautrius terapinius produktus, gamybai. Pagrindinės savybės: - Vienkartiniai srautai – pašalinamas poreikis valyti ir tikrinti valymo efektyvumą tarp ciklų, sumažinamas prastovų laikas ir kryžminės taršos rizika. - Lankstus veikimas – galimi įvairūs konfigūracijų variantai (izokratinė, gradiento, su UV kontrole, išplėsta) pagal skirtingus valymo poreikius. - Skalėje plečiama platforma – mažo ir didelio srauto rinkiniai palaiko platų procesų apimčių spektrą; sistema gali būti pritaikoma nuo mažų partijų iki didesnių gamybos mastų, naudojant didesnius ÄKTA ready™ XL modelius. - Sukurta GMP aplinkai – gausi dokumentacija ir atitikties palaikymas padeda atitikti biologinių vaistų gamybai taikomus reguliacinius reikalavimus.

Būklė: labai geros būklės (naudotas), Teledyne Isco CombiFlash Companion/TS The CombiFlash Companion personal flash chromatography system can be controlled and monitored from anywhere with any internet connection and Microsoft Windows® Explorer. It even notifies you by email once the separation is complete. The system’s advanced automation and communication features offer maximum productivity and carefree operation, allowing you to focus on other tasks while purification is underway. You can also operate the system locally via the touchscreen controller, which offers a clear and user-friendly interface. The optional solvent management module controls up to four solvents online and monitors their levels, ensuring you never run out of solvent. The Companion uses precision-packed RediSep® Rf columns to obtain more purified material in a shorter time compared to glass columns or other disposable columns. Columns from 4 g up to 330 g can be quickly exchanged without additional hardware, making it easy and fast to scale up from milligrams to several tens of grams of purified sample. Hnjdpfjyk Enaox Afton The CombiFlash Companion automatically detects column size and self-programs the optimal conditions for that column. To start a run, simply press “Play.” Since the software is designed specifically for purification (not analysis), you can modify method parameters in real time. To adjust the gradient during a run, simply click on a point in the gradient profile and drag it to the desired value to instantly modify the solvent mixture. Power supply: 100/117 V AC, 50/60 Hz; 234 V AC, 50/60 Hz Dimensions (D x H x W): 540 x 490 x 490 mm Weight: 27.2 kg See more new and used items in our shop! International shipping costs on request!

Būklė: naujas, Gamybos metai: 2020, Funkcionalumas: visiškai funkcionalus, Įranga: dokumentacija / vadovas, Manufacturer: BRINOX Type: LEP 11 – CIP-Skid Year of manufacture: 2020 Design: Pharma / GMP Condition: New, unused, in original packaging LEP 11 CS6710 Package 1 Machine Type Pharmaceutical CIP System (Cleaning in Place) as a compact package unit mounted on a stainless steel frame. Hedpfxeyl Hwle Aftjnn Application Automated cleaning of process equipment, chromatography systems, tanks, and piping in the pharmaceutical, biotech, and chemical industries. Suitable for NaOH, acetic acid, WFI, PW, and other cleaning media. Technical Data Heating capacity for CIP medium: From +5°C to +80°C in max. 10 minutes Pump capacity: 1 – 4 m³/h (adjustable) Operating pressure at CIP supply: 1 – 3 bar (adjustable) Measuring ranges: Flow rate: 0 – 10 m³/h Temperature: 0 – +150°C Pressure: 0 – 6 bar Design pressure: -0.9 to +6 bar Design temperature: +2 to +95°C Construction • Compact package unit on stainless steel frame • CIP supply pump as centrifugal pump • Shell-and-tube heat exchanger with leak-proof transfer • Height-adjustable dome feet • Fully drainable design • Maintenance-friendly setup • Industrial high-performance construction Material & GMP Design • Product and cleaning media-contact parts made of stainless steel 1.4435 • Electropolished surfaces Ra ≤ 0.8 µm • FDA-compliant seals (EPDM / PTFE / silicone) • Designed for NaOH 0.3 mol/L at +80°C • Resistant to acetic acid, WFIH, WFIC, PUW Documentation & Quality • Complete GMP documentation • CE compliance • 3.1 material certificates • Complete welding records • Weld seam documentation including photographic evidence • Documented pressure and leak tests • FAT documentation available • Drainability and final rinse certificates available Condition • New • Unused • Original packaging • Zero operating hours • Immediately available Special Features • Very high thermal cleaning efficiency • Fully adjustable process control • Top-tier pharma GMP execution • High-quality European components • Investment-safe system with complete documentation Location: Germany Inspection possible by appointment

Gamybos metai: 2022, būklė: naudotas, Šis pasiūlymas skirtas Cytiva AKTA Avant 150 chromatografijos sistemai. Įrenginys puikios būklės, naudotas tik apie 2 metus. Hnodpfxsyk Erxe Aften Cytiva AKTA Avant 150 chromatografijos sistema – tai stalinis preparatinės chromatografijos įrenginys, kuris daugiausia naudojamas baltymų gryninimui, metodų kūrimui ir procesų mastelio didinimui moksliniuose tyrimuose bei biofarmacijos srityje. Tai – Cytiva ÄKTA šeimos FPLC (greitos baltymų skystosios chromatografijos) įranga, sukurta automatizuotam, atkuriamam biomolekulių atskyrimui. Šis instrumentas idealiai tinka: - Baltymų ir antikūnų gryninimui moksliniuose tyrimuose bei ankstyvose bioprocesų stadijose. Bionex Scientific - Procesų vystymui ir metodų optimizavimui prieš pradedant didelio masto gamybą. Cytiva - Kolonėlių užpildymui ir įvertinimui, ypač pasiruošiant chromatografijos mastelio plėtrai. SelectScience - Biomolekulių atskyrimo procesams biotechnologijos, biochemijos ir analitinėse laboratorijose. Bionex Analytical

Būklė: naudotas, Šiame pasiūlyme parduodama ÄKTA ready™ chromatografijos sistema Įrenginys yra visiškai veikiantis ir paruoštas nedelsiant naudoti. ÄKTA ready™ chromatografijos sistema – tai vienkartinio naudojimo skysčių chromatografijos platforma, sukurta bioprocesams, procesų mastelio didinimui ir GMP reikalavimus atitinkančiai biologinių vaistų, įskaitant monokloninius antikūnus, rekombinantinius baltymus, virusinius vektorius, nukleorūgštis ir kitus jautrius terapinius produktus, gamybai. Pagrindinės savybės: Hnodpfx Afoyitvpjtjn - Vienkartiniai srautai – pašalinamas poreikis valyti ir tikrinti valymo efektyvumą tarp ciklų, sumažinamas prastovų laikas ir kryžminės taršos rizika. - Lankstus veikimas – galimi įvairūs konfigūracijų variantai (izokratinė, gradiento, su UV kontrole, išplėsta) pagal skirtingus valymo poreikius. - Skalėje plečiama platforma – mažo ir didelio srauto rinkiniai palaiko platų procesų apimčių spektrą; sistema gali būti pritaikoma nuo mažų partijų iki didesnių gamybos mastų, naudojant didesnius ÄKTA ready™ XL modelius. - Sukurta GMP aplinkai – gausi dokumentacija ir atitikties palaikymas padeda atitikti biologinių vaistų gamybai taikomus reguliacinius reikalavimus.

Būklė: naudotas, tuščias svoris: 9 762 kg, bendras svoris: 39 000 kg, ašių konfigūracija: 3 ašys, pirmoji registracija: 06/2020, krovimo vietos ilgis: 13 403 mm, krovinių skyriaus plotis: 2 490 mm, krovos erdvės aukštis: 2 650 mm, krovinio erdvės tūris: 88 m³, pakaba: oras, padangos dydis: 385/55 R22,5, spalva: balta, Gamybos metai: 2020, Įranga: ABS,

Būklė: naudotas, tuščias svoris: 9 762 kg, ašių konfigūracija: 3 ašys, pirmoji registracija: 06/2020, pakaba: oras, Gamybos metai: 2020, Įranga: ABS,

Būklė: naujas, Gamybos metai: 2020, Funkcionalumas: visiškai funkcionalus, Įranga: dokumentacija / vadovas, For sale is a fully sourced, modular GMP process system for manufacturing C1-Esterase Inhibitor (C1-INH) from human plasma. The plant has been engineered, procured, and FAT-tested in full, but has never been installed or put into operation. This is explicitly not a used line, but a brand-new project and module package. Year of manufacture: 2020 Condition: factory-new, original packaging Operating hours: 0 Storage: climate-controlled warehouse SYSTEM SCOPE (EXCERPT WITH QUANTITIES) Adsorption / Chromatography (Bay 2 & 3): – 2 adsorption lines (DEAE / QAE) – 2 intermediate tanks – 2 pigging systems – 2 cooled transfer lines (pipe-in-pipe) – 4 filter press racks – 4 cooling cascades – 4 CIP loops Precipitation PRE: – 3 pre-precipitation tanks (incl. 1,000 L) – 3 main precipitation tanks – 3 CIP stations – 3 multi-layer filters – 1 vacuum station Buffer Preparation (Bay 2 & 3): – 6 buffer tanks (NaCl, DEAE, QAE buffer) – 6 temperature control skids – 4 media/WFI/CIP manifolds LEP 2.3 – Washing & Elution Solutions: – 2 washing solution tanks (up to 9,000 L) – 2 elution solution tanks – 4 temperature control units LEP 13 – Ammonium Sulfate System: – 1 preparation tank (3,500 L) – 2 storage/distribution tanks – solids breaker – dosing & neutralization system – trace-heated piping Media Distribution: – 1 pharmaceutical NaOH 1M system – 1 technical NaOH 32% system – 1 acetic acid 60% system – pump and dosing stations Additional Process Vessels: – >15 stainless steel vessels 316L (1,000–9,000 L) – various skids, manifold, and instrumentation units GMP & DOCUMENTATION – URS / requirement specifications per LEP – P&ID flow diagrams – layout & section drawings – EMSR & instrumentation documentation – FAT documentation – complete weld seam documentation (digital) – extensive photo documentation The project documentation is available in full—digitally and additionally physically archived in 316 organized folders. PLC integration with prepared MES interface is provided. Cleanroom integration according to specification. Hedpfx Afeym Ayfjtjnn SALE Preferably as a complete system. Modular sale possible if a total sale is not realized. Suitable for plasma fractionators, biopharmaceutical manufacturers, CDMOs, or new site development projects. Availability: short notice Inspection: by appointment Price: on request

Būklė: naujas, Gamybos metai: 2020, Funkcionalumas: visiškai funkcionalus, Įranga: dokumentacija / vadovas, BRINOX LEP13.2 – AS Storage Tempering Unit – GMP – Year 2020 – as new Manufacturer: BRINOX Process Systems LEP13.2 KK6772 Package 12 System type: LEP13.2 – AS Storage Tempering Unit Project: Ammonium Sulphate System Year of manufacture: 2020 Serial number: 1003624 Tag number: MR-ASF-ASF61-KK6772 Location: Germany DESCRIPTION Hedpfx Afjyl Na Netonn For sale is an as-new tempering unit LEP13.2 in pharmaceutical GMP-certified design, manufactured by BRINOX Process Systems. The unit is constructed as a compact, pre-assembled skid unit and was designed for use in an ammonium sulphate storage system. Complete project and FAT documentation is available. TECHNICAL DATA Type: LEP13.2 – AS Storage Tempering Unit Medium: Ammonium sulphate Design: Pharma / GMP Materials: Stainless steel 1.4435 / 1.4301 Control air supply: 6 bar Pressure and leak tests performed FAT successfully completed MAIN COMPONENTS - 2x KSB Movitec centrifugal pumps - Alfa Laval plate heat exchanger - Electric inline heater - Reflex expansion vessel - Samson control valve - GEMÜ ball valves (manual & pneumatic) - Labom pressure gauge - Extensive sensors & measuring instruments - Insulated piping - Stainless steel skid frame construction APPLICATIONS - Tempering of process media - Use in GMP-regulated production areas - Pharmaceutical and biotechnology plants - Media circuits with temperature control CONSTRUCTION - Compact, closed skid unit - Fully piped - Professionally insulated piping - High-quality industrial components - Service-friendly layout - Fully demountable and transportable CONDITION Condition: New, original packaging Year of manufacture: 2020 Project unit Minimal operating hours Excellent visual and technical condition DOCUMENTATION - FAT documentation - Pressure test protocols - P&ID schematics - Layout drawings - Factory certificates according to EN10204 - Parts lists - EU Declarations of Conformity FEATURES - Complete GMP documentation - Premium branded components - Ideal for pharmaceutical and biotech applications - Immediately available - Significantly below new price

Būklė: naujas, Gamybos metai: 2020, Funkcionalumas: visiškai funkcionalus, Įranga: dokumentacija / vadovas, Manufacturer: BRINOX Process Systems Hnjdpfx Aeyl I S Doften LEP13.2 KK6771 Package 11 System type: Temperature control unit – LEP13.2 AS storage Project: Ammonium sulfate supply and disposal Plant: KK6771 Year of manufacture: 2020 Serial number: 1003622 Equipment number: 20022749 LEP13.2 – AS Storage Temperature Control Unit TECHNICAL DATA Product: LEP13.2 – AS Storage Temperature Control Unit Medium: Ammonium sulfate Design: Pharmaceutical / GMP Product-contact materials: 1.4435 / 1.4301 Dimensions (L x W x H): approx. 1900 x 1545 x 1580 mm Control air pressure: 6 bar (AIP) Tested pressure range: up to approx. 3–4 bar (leak test documented) MAIN COMPONENTS 2x centrifugal pumps Shell-and-tube heat exchanger (horizontal) Electric instantaneous water heater Expansion vessel Pressure and temperature measurement points Pneumatic control valves Manual ball valves (GEMÜ) Stainless steel control cabinet / terminal box Fully insulated piping APPLICATION The temperature control unit is used for precise temperature regulation in the ammonium sulfate storage system at a pharmaceutical production site. Suitable for: Pharmaceutical production environments GMP-regulated plants Media temperature control systems Turn-over package integration DESIGN / CONSTRUCTION Complete, pre-assembled skid unit Stainless steel frame construction Compact design with free maintenance access Completely piped and insulated Clear labeling of all measuring points and valves Pharmaceutical specification according to CSL Behring customer requirements P&ID tested Layout tested Multiple documented leak tests Calibrated measuring instruments with certificates The plant is fully assembled and prepared for integration into existing pharmaceutical systems. CONDITION As new / project system Year of manufacture: 2020 FAT performed Pressure test passed Complete documentation available DOCUMENTATION (EXTENSIVE) Included, among others: Factory certificates according to EN 10204 Material lists EU declarations Test reports Documentation of installed equipment Instrumentation documentation As-built isometrics User manual Calibration certificates SPECIAL FEATURES Project-specific pharmaceutical design GMP-compliant manufacturing Complete skid-mounted configuration Compact footprint (approx. 1.9 x 1.5 m) Maintenance-friendly design High-quality insulation of piping Ideal for technical areas close to cleanrooms

Būklė: naujas, Gamybos metai: 2020, Funkcionalumas: visiškai funkcionalus, Įranga: dokumentacija / vadovas, Manufacturer: BRINOX Product: LEP13.1 – AS Batch Temperature Control Unit System Type: Temperature Control Unit for Ammonium Sulfate Batch Systems Year of Manufacture: 2020 Serial Number: 1003620 Tag Number: MR-ASF-ASF61-KK6770 Equipment Number: 20022748 Media Connections / Process Data WCOV – Chilled Water Supply: 6°C WCOR – Chilled Water Return: 12°C WSV – Service/Town Water AIP10 – Control Air Pressure: 6 bar Design as a closed temperature control module with integrated pump and heat exchanger technology. Dimensions Overall dimensions according to layout: approx. 1920 x 1435 x 1573 mm (L x W x H) Compact, skid-mounted unit with welded stainless steel frame. Construction - Frame made of stainless steel - Fully insulated piping (industrial insulation) Hodeyl Izxopfx Aftjnn - Stainless steel shell-and-tube heat exchanger - Electric instantaneous water heater WT1011 - Pump PU1021 - Pump PU9203 - Heat exchanger WT1001 - Expansion vessel BH9701 Fittings: - GEMÜ isolation valves - Pneumatically actuated valves - Manual ball valves - Pressure gauges - Sensor technology and measuring points as per P&ID Complete piping and component identification present. Condition - New and originally packaged - Not commissioned in production operation - Factory New Condition - Supplied directly from manufacturer Brinox FAT / Test Status FAT performed Leak Test: - Test medium: Compressed air - Test pressure: approx. 3 bar - Hold time: 1 hour - Result: Passed Calibration: - Pressure gauge calibrated - Measuring range: 0–10 bar - Calibration certificate available - Traceable to national standards Documentation Complete Turn-Over Package Included documents: - FAT plan - FAT report - Non-conformity form - Layout drawing review - Maintenance and calibration accessibility review - P&ID diagram review - Leak test protocol - Calibration certificates - Documentation review Factory certificate 2.1 according to EN 10204 LBM material list incl. EU declarations Installed components list – equipment Installed components list – E&I points Material part list for as-built isometrics Special Features - GMP-compliant design - Pharma/biotech project quality - Full traceability - Compact plug-and-play skid design - Fully piped, insulated, and ready to connect - Immediately available

Būklė: naujas, Gamybos metai: 2020, Funkcionalumas: visiškai funkcionalus, Įranga: dokumentacija / vadovas, Manufacturer BRINOX d.o.o. Project Number B-0001113-LEP2.3 LEP 2.3 KK6762 Package 9 Module M024 Product Description LEP2.3 – Washing Solution Tempering Unit Serial Number 1003572 Equipment Number 20022782 Tag Number MR-INH-VPR61-KK6762 Year of Manufacture 2020 Technical Data System Type Pharma tempering skid for precise temperature control of washing and elution solutions. Constructed as a compact, multi-level stainless steel frame with fully integrated pump, heat exchanger, and valve technology. Dimensions Length: 1920 mm Width: 1365 mm Height: 1840 mm Design Fully pre-assembled, insulated tempering skid Pharmaceutical-grade construction in accordance with GMP requirements Industrial stainless steel frame construction Materials Product-contact parts: Stainless steel 1.4435 / 1.4571 Frame construction: Stainless steel 1.4301 Welding in accordance with EN ISO 13920 D Insulation Completely insulated piping and apparatus Closed-cell high-performance insulation with black protective jacket Main Components PU1021 Process Pump PU9203 Cooling Medium Pump WT1001 Plate Heat Exchanger WT1011 Finned Tube Heat Exchanger BH9701 Expansion Vessel Pneumatic Control Valves GEMÜ Stainless Steel Ball Valves Pressure Transmitter Temperature Measuring Points Pressure Gauge Electrical Terminal Box with Warning Labeling Stainless Steel Cable Trays Media Chilled Brine, Supply/Return Washing Solution Process Medium Control Air 6 bar All media connections are factory-sealed and packed for safe transport. Leak Testing Performed as pressure tests with compressed air. DP-01 Medium: Compressed Air Test Pressure: 3.15 bar Pressure Drop: 0.13 bar Date: 27.07.2020 Hodpfjyl Iwtex Aftonn Result: Passed DP-02 Medium: Compressed Air Test Pressure: 3.28 bar Pressure Drop: 0.07 bar Date: 26.07.2020 Result: Passed Pressure hold time: 1 hour each No leaks detected Calibration Certificates Calibration Laboratory: LOTRIČ Metrology Certificates in accordance with EN ISO/IEC 17025 Measuring Ranges: –1 to 20 bar and 0 to 10 bar Calibration performed Scope of Documentation FAT plan and report Deviation form Layout drawing inspection Maintenance inspection P&ID Leak test Calibration certificates 2.1 Factory Certificate EN10204 Material list As-built isometric drawing Complete turn-over package Inspection Status FAT performed Pressure test passed Calibrations available PED-compliant design Complete pharmaceutical documentation Application Temperature control of washing and elution solutions in biopharmaceutical production plants Suitable for GMP environments Condition New system Originally packed Unused Year of manufacture: 2020 Factory condition Fully documented Immediately available

Būklė: naujas, Gamybos metai: 2020, Funkcionalumas: visiškai funkcionalus, Įranga: dokumentacija / vadovas, Manufacturer: BRINOX Type: LEP2.3 – Washing Solution Temperature Control Unit Year of construction: 2020 Serial number: 1003507 LEP2.3 KK6761 Package 8 Tag No.: MR-INH-VPR61-KK6761 Hnodpfx Afoyl It Ijten Equipment No.: 20023781 Technical Data System type: Temperature control unit / heating and cooling module for washing solution (CIP or process washing system) Design: Compact, fully pre-assembled skid unit with robust stainless steel frame construction, craneable via integrated lifting points. Frame and Construction: Welded stainless steel industrial frame, free-standing, multi-level piping arrangement for optimal space utilization. Maintenance-friendly accessibility from multiple sides. Integrated cable trays. Piping: Stainless steel process piping in hygienic design, welded and partially flanged. Multilayer thermal insulation for main lines and equipment. Integrated drain and vent fittings. Valve Technology: Several manual ball valves (GEMÜ) in main and bypass lines. Pneumatically actuated control and shut-off valves for automatic temperature regulation. Diaphragm and control valves integrated in heating and cooling circuits. Measurement and Control Technology: Temperature measuring points in supply and return lines. Pressure sensors in the process line. Integrated flow measurement. Electrical junction box with protective labelling. Automatic temperature control via pneumatic control valve. Heat Exchanger: Cylindrical stainless steel heat exchanger, insulated and integrated into the piping system. Designed for controlled heating and/or cooling of the washing solution in a closed circuit. Pump Technology: Two electrically driven centrifugal pumps with red lacquered motors for process recirculation within the temperature control unit. Electrical: Electrical junction box with warning label. Wired sensors and actuators. Prepared for integration into an overriding control or process control system. Application The unit is used for precise temperature control of a washing solution within a pharmaceutical or biotechnological process system. Typical areas of application include CIP systems, wash stations for production equipment, and temperature-controlled cleaning processes in pharmaceutical and biotechnological industries. The washing solution is circulated in a closed loop via pumps, temperature controlled by the integrated heat exchanger, and continuously monitored by sensors. Temperature regulation is automatic via pneumatic control valves for precise adherence to defined setpoints. Construction Compact modular skid design with fully insulated main lines. Stainless steel surfaces in hygienic industrial finish. Clear media routing and structured piping layout. Crane-transportable via integrated lifting points. Condition Year of construction: 2020. Very good visual and technical condition. Professional execution for pharmaceutical plant engineering. FAT / Documentation Typically supplied with CE conformity, factory acceptance test (FAT), and technical documentation including P&ID diagrams and material certificates for product-contact components. Special Features Fully insulated temperature control module in a compact design with high power density. Premium valve technology (GEMÜ). Multiple integrated measuring and control points. Suitable for validated pharmaceutical processes. Industrial pre-assembled skid solution with clearly structured media flow.

Būklė: naujas, Gamybos metai: 2020, Funkcionalumas: visiškai funkcionalus, Įranga: dokumentacija / vadovas, Manufacturer: BRINOX Process Systems Type: LEP 2.3 System type: Temperature control unit for wash and elution solutions Year of manufacture: 2020 Serial number: 1003563 Device number: KK6752 Design: Stainless steel skid, pharmaceutical-grade construction LEP 2.3 KK6752 Package 7 Technical Data Design: Compact, pre-assembled temperature control skid on a welded stainless steel frame (skid system) Materials: Product-contact surfaces: Stainless steel 1.4435 / 1.4404 Non-product-contact surfaces: Stainless steel 1.4301 Piping system: Orbital welding (pharmaceutical grade) Fully welded design As-built isometric drawings available Pressure data: Leak test with compressed air Test pressure: 3.37 bar Hold time: 1 hour Result: Leak-free Measurement and control technology: Pressure measurement (PIR, PI, PIRC) Temperature measurement (TI, TIRC) Level measurement (limit value) Flow monitoring Position feedbacks Motor control On/off pneumatic valves Pressure sensor measuring range: 0–10 bar Electrical connection: Control air: 6 bar Automation-ready (PLT points fully documented) Main components: 2 process pumps Plate heat exchanger Finned tube heat exchanger Expansion vessel Hnodpfx Afsyl Ipcjton Multiple hygienic control and shut-off valves Integrated instrumentation units Cooling medium: Cooling brine (inlet/outlet interfaces available) ───── Dimensions / Weight Design: Compact skid unit Industrial-grade for cleanroom/technical areas (Transport and installation dimensions according to layout drawing) Application Area Temperature control for: Washing solutions Elution solutions Process media in biopharmaceutical environments Fields of application: Biotechnology Plasma fractionation GMP production facilities Construction / Configuration Welded stainless steel frame Low-vibration pump installation Hygienic piping layout Full implementation according to P&ID Clear separation of product and non-product areas Service and maintenance accessibility verified Mechanical SAT-IQ test performed Metrological SAT-IQ test performed P&ID (R&I) diagram review completed Layout drawing review completed Condition Year of manufacture 2020 Industrial and pharmaceutical grade Brand new, original packaging Pressure tested Sensors calibrated FAT performed FAT / Documentation Available: FAT plan and report Deviation management Layout review P&ID (R&I) review Leak test Sensor calibration Maintenance and accessibility review EN10204 factory certificate Material lists (LBM) As-built isometric drawings Component lists (equipment & PLT points) Special features Pharma GMP-compliant design Complete validation documentation Full traceability Certified pressure testing Calibration certificates from accredited laboratories High-quality plant engineering by BRINOX High-end biopharma standard

Būklė: naujas, Gamybos metai: 2020, Funkcionalumas: visiškai funkcionalus, Įranga: dokumentacija / vadovas, Manufacturer: BRINOX Type: LEP 2.3 – Wash Solution Temperature Control Unit Year of Manufacture: 2020 Serial Number: 1003561 Tag Number: MR-INH-VPR61-KK6751 Equipment Number: 20022779 Location: Germany Condition: New, unused, original packaging Technical Data System Type: Wash Solution Temperature Control Unit (Temperature Control Skid) Design: Compact, pre-assembled skid unit in stainless steel frame Frame Material: Stainless steel Insulation: Completely insulated piping and components Pumps: Two circulation pumps with electric motor Stainless steel pump housing Inline configuration Heat Exchanger: Integrated stainless steel heat exchanger Shell-and-tube design Valves: Multiple GEMÜ ball valves Stainless steel valves Pneumatic control valves Safety valves Measuring Technology: Pressure transmitter Pressure gauges Temperature measuring points Integrated flow measurement Electrics: Integrated control cabinet/terminal box Wired ready for connection Industrial standard components Piping: Stainless steel process piping Fully insulated Flange and clamp connections Transport: Forklift and crane compatible Robust stainless steel base frame Application The temperature control unit is designed for controlled thermal management of a wash solution within pharmaceutical or chemical processes. Hjdpsyl Ib Eefx Aftjnn Suitable for CIP and washing processes, pharmaceutical production lines, chemical process plants as well as temperature-regulated media circuits. Construction Compact, modular skid design Pre-assembled and ready for connection High-quality stainless steel fabrication Industrial-grade components, including GEMÜ valves Service-friendly construction Condition New system Never commissioned Original packaging Directly from manufacturer’s project Immediately available FAT and Documentation Status Technical documentation available Project documentation available Drawings available P&ID available Component lists available Operating manual available Key Features Completely insulated process piping High-quality stainless steel design Industrial brand components Ideal for new projects or as a replacement/redundancy unit Immediate integration possible

Būklė: naujas, Gamybos metai: 2020, Funkcionalumas: visiškai funkcionalus, Įranga: dokumentacija / vadovas, Machine Description BRINOX LEP 12 – CIP System Precipitation PRE LEP 12 CS6725 Package 5 Manufacturer BRINOX Prozess- und Edelstahltechnik GmbH, Offenburg Year of Manufacture 2020 Serial Number 1003614 Technical Data Compact CIP skid unit in stainless steel frame construction. Product designation: LEP 12 – CIP System Precipitation PRE. Dimensions approx. 1520 x 970 x 1994 mm. Product-contact materials: Stainless steel 1.4435. Frame and structural components: Stainless steel 1.4301. Integrated shell-and-tube heat exchanger by NEUMO. Centrifugal pump in hygienic design. All pipework fully welded, pharmaceutical specification. Insulated media lines. Fittings including GEMÜ ball valves. Various integrated pressure gauges and instrumentation. Calibrated pressure measurement system (Fluke pressure transducer, measuring range −1 to 20 bar, resolution 0.001 bar, accuracy 0.06% FS). Hjdoyl H Taspfx Aftonn Media connections: NaOH Acetic acid CIP supply CIP return Black steam Black steam condensate Neutralized wastewater Leak test performed with compressed air. Test pressure range approx. 3.19–3.24 bar. Maximum recorded pressure drop < 0.015 bar during the test period. Result: passed. Application CIP cleaning system for pharmaceutical process plants, especially for precipitation tanks. Suitable for caustic and acid cleaning cycles as well as steam connection. Designed for hygienic applications in pharmaceutical production. Construction Welded, compact skid design with robust stainless steel frame construction. Hygienic piping with defined media routes. Integrated shell-and-tube heat exchanger for temperature control of CIP media. Integrated process pump, valve technology and instrumentation on a compact frame. General tolerances in accordance with EN ISO 13920. Industrial design with crane lifting lugs for transport. Condition New, unused, original packaging. System was exclusively tested as part of Factory Acceptance Test (FAT) and has not been operated in production. FAT / Documentation status Complete Factory Acceptance Tests performed. Leak tests successfully passed. Calibration certificates available. Test protocols fully documented. Complete Documentation List FAT documentation Leak test protocols Calibration certificates P&ID 3D drawings Material and welding documentation Nameplate and manufacturer documentation Key Features Pharma-grade material selection. Compact, ready-to-use skid unit. High-quality components from renowned manufacturers. Full technical documentation available. Immediately available.