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Symex CML500

The Symex CML 500 is a powerful vacuum homogenizer mixer designed for the production of sophisticated products in the pharmaceutical and cosmetics industries.

The system combines mixing, dispersing, homogenizing, heating, cooling, and vacuum processing within a closed unit, thus enabling precise and reproducible production—from pilot scale to industrial application. These systems are specifically engineered for complex processes with high quality requirements.

Technical Highlights of the Symex CML 500

Vessel
- Working volume: approx. 500 litres
- Total volume: approx. 780 litres
- Minimum volume: approx. 125–160 litres
- Product chamber pressure range: -1 / +2 bar
- Product temperature: up to approx. 133 °C
- Heating jacket: up to +4 bar / 151 °C
- Manufactured according to AD 2000 standards
- The vessel is fully rated for pressure and vacuum operation, enabling safe processing under demanding conditions.

Agitator
- Anchor agitator with flow breakers
- Speed range: approx. 11–66 rpm
- Power: approx. 7.5 kW
- Frequency-controlled
- Designed for highly viscous products
- The agitator ensures homogeneous mixing and optimal heat transfer.

Homogenizer
- Power: approx. 16–20 kW
- Speed: up to approx. 3,000 rpm
- High shear performance for fine dispersion
- Rotor/stator system
- The homogenizer reliably provides stable emulsions and consistent product qualities.

Vacuum System
- Operation under vacuum possible
- Liquid ring vacuum pump (external)
- Pressure and vacuum monitoring
- Vacuum operation significantly reduces air intake and improves product quality.

Heating & Cooling
- Double-walled vessel (2-zone heating)
- Precise temperature control
- Even heat distribution
- CIP (Clean-In-Place) system

Multiple CIP Connections
- Rotating spray heads (360°)
- Full chamber cleaning, including piping

Raw Material Intake
- Direct suction of liquids and powders
- Intake directly into the homogenizer zone
- Fast, low-loss processing
- Such integrated intake and recirculation systems enable highly efficient process management.

Additional Features
- Hydraulic lid lifting device
- Multi-port bell with several connection options
- Sight glass with dual wipers
- Vessel lighting
- Dosing vessel (approx. 8 litres)
- Sampling valve
- Membrane and disc valves
- Recirculation lines for homogenization and CIP
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- Control & Operation

The system is equipped with a modern operating concept:
- Touch screen control panel
- Adjustable speed and runtimes
- Process monitoring (pressure, temperature, speed)
- Automatic and manual operation modes
- Fault messages and safety functions

Advantages of the Symex CML 500
- Integration of all process steps in one system
- High process reliability due to closed design
- Reproducible and stable product quality
- Suitable for highly viscous and sensitive products
- Hygienic design (GMP-compliant)
- Flexible for various batch sizes

Delivery & Handling
- Delivery ex-works
- Turn-key project available (including commissioning)
- International shipping possible

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